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1

The chemistry of clavulanic acid: Some reactions of esters under neutral, acidic and basic conditions

Allan G. Brown, T.Trefor Howarth, Roger J. Ponsford

Journal:

Tetrahedron Letters

Year:

1983

Language:

english

File:

PDF, 231 KB

english, 1983

2

Structures of olivanic acid derivatives MM 4550 and MM 13902; two new, fused ?-lactams isolated from Streptomyces olivaceus

Brown, Allan G., Corbett, David F., Eglington, A. John, Howarth, T. Trefor

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1977

Language:

english

File:

PDF, 242 KB

english, 1977

3

Studies related to the structures of the olivanic acids MM 13902, MM 4550 and MM 17880 : Three β-lactam antibiotics from streptomyces olivaceus

Allan G. Brown, David F. Corbett, A.John Eglington, T.Trefor Howarth

Journal:

Year:

1983

Language:

english

File:

PDF, 1.59 MB

english, 1983

4

The formation and x-ray crystal structure analysis of isoclavulanic acid

Allan G. Brown, T.Trefor Howarth, Irene Stirling, Trevor J. King

Journal:

Tetrahedron Letters

Year:

1976

Language:

english

File:

PDF, 102 KB

english, 1976

5

Clavulanic acid. Rearrangement to 3, 4-disubstituted pyrroles

J.Sydney Davies, T.Trefor Howarth

Journal:

Tetrahedron Letters

Year:

1982

Language:

english

File:

PDF, 200 KB

english, 1982

6

Pyrroles and related compounds. Part XXVI. Pyrrole ?-keto-esters

Howarth, T. Trefor, Jackson, Anthony H., Judge, Jean, Kenner, George W., Newman, David J.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1974

Language:

english

File:

PDF, 1.80 MB

english, 1974

7

Clavulanic acid, a novel ?-lactam isolated from Streptomyces clavuligerus; X-ray crystal structure analysis

Howarth, T. Trefor, Brown, Allan G., King, Trevor J.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1976

Language:

english

File:

PDF, 170 KB

english, 1976

8

Preparation and biogenetic-type aromatizations of tetraacetic acid (3,5,7-trioxooctanoic acid)

Howarth, T. Trefor, Murphy, George P., Harris, Thomas M.

Journal:

Journal of the American Chemical Society

Year:

1969

Language:

english

File:

PDF, 259 KB

english, 1969

9

Models of the biogenesis of polyketide-type phenolic ethers

Harris, Thomas Munson, Howarth, T. Trefor, Carney, Robert L.

Journal:

Journal of the American Chemical Society

Year:

1971

Language:

english

File:

PDF, 681 KB

english, 1971

10

Biogenetic-type synthesis of .beta.-resorcylic acids. Isolation and characterization of the aldol intermediate

Harris, Thomas Munson, Howarth, T. Trefor

Journal:

Journal of the American Chemical Society

Year:

1971

Language:

english

File:

PDF, 632 KB

english, 1971

11

Oxidation of clavulanic acid and a ready synthesis of the 7-oxo-4-oxa-1-azabicyclo[3.2.0]hept-2-ene ring system

Corbett, David F., Howarth, T. Trefor, Stirling, Irene

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1977

Language:

english

File:

PDF, 103 KB

english, 1977

12

Wittig reactions with ?-lactam carbonyls: a convenient means of protection. X-Ray crystal structure of p-nitrobenzyl-(2R,5R)-Z-7-methoxycarbonylmethylene-Z-3-(?-phthalimidoethylidene)-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylate

Gilpin, Martin L., Harbridge, John B., Howarth, T. Trefor, King, Trevor J.

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1981

Language:

english

File:

PDF, 194 KB

english, 1981

13

Clavulanic acid and its derivatives. Structure elucidation of clavulanic acid and the preparation of dihydroclavulanic acid, isoclavulanic acid, esters and related oxidation products

Brown, Allan G., Corbett, David F., Goodacre, Jennifer, Harbridge, John B., Howarth, T. Trefor, Ponsford, Roger J., Stirling, Irene, King, Trevor J.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1984

Language:

english

File:

PDF, 2.45 MB

english, 1984

14

Novel synthesis of the 7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane ring system

Brown, Allan G., Corbett, David F., Howarth, T. Trefor

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1977

Language:

english

File:

PDF, 165 KB

english, 1977

15

Structure elucidation of MM 17880, a new fused ?-lactam antibiotic isolated from Streptomyces olivaceus; a mild ?-lactam degradation reaction

Corbett, David F., Eglington, A. John, Howarth, T. Trefor

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1977

Language:

english

File:

PDF, 153 KB

english, 1977

16

Synthesis of ethyl 3-methyl-7-oxo-4-oxo-4-oxa-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate and the reaction of 4-acetoxyazetidin-2-one with ethyl ?-diazoacetoacetate

Brooks, Gerald, Howarth, T. Trefor, Hunt, Eric

Journal:

Journal of the Chemical Society Chemical Communications

Year:

1981

Language:

english

File:

PDF, 140 KB

english, 1981

17

Methyl 2-hydroxy-4-methoxy-6-phenylbenzoate and methyl 2-hydroxy-6-methoxy-4-phenylbenzoate: reassignment of a structure

Howarth, T. Trefor, Harris, Thomas M.

Journal:

Canadian Journal of Chemistry

Year:

1968

Language:

english

File:

PDF, 212 KB

english, 1968

18

Nuclear modification of clavulanic acid. Preparation of optically active 1-oxaceph-3-ems

Brooks, Gerald, Gasson, Brian C., Howarth, T. Trefor, Hunt, Eric, Luk, Kong

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1984

Language:

english

File:

PDF, 729 KB

english, 1984

19

ChemInform Abstract: PYRROLES AND RELATED COMPOUNDS PART 28, BETA-KETO-ESTERS IN THE PORPHYRIN SERIES

COX, MICHAEL T., HOWARTH, T. TREFOR, JACKSON, ANTHONY H., KENNER, GEORGE W.

Journal:

Chemischer Informationsdienst

Year:

1974

File:

PDF, 155 KB

1974

20

ChemInform Abstract: PYRROLES AND RELATED COMPOUNDS PART 27, SYNTHESES OF PORPHYRINS WITH A NUCLEAR CARBOXY-GROUP

HOWARTH, T. TREFOR, JACKSON, ANTHONY H., KENNER, GEORGE W.

Journal:

Chemischer Informationsdienst

Year:

1974

File:

PDF, 170 KB

1974

21

Pyrroles and related compounds. Part XXVII. Syntheses of porphyrins with a nuclear carboxy-group

Howarth, T. Trefor, Jackson, Anthony H., Kenner, George W.

Journal:

Journal of the Chemical Society Perkin Transactions 1

Year:

1974

Language:

english

File:

PDF, 1.58 MB

english, 1974

22

ChemInform Abstract: PYRROLES AND RELATED COMPOUNDS PART 26, PYRROLE BETA-KETO-ESTERS

HOWARTH, T. TREFOR, JACKSON, ANTHONY H., JUDGE, JEAN, KENNER, GEORGE W., NEWMAN, DAVID J.

Journal:

Chemischer Informationsdienst

Year:

1974

Language:

german

File:

PDF, 264 KB

german, 1974

23

ChemInform Abstract: PYRROLES AND RELATED COMPOUNDS PART 26, PYRROLE BETA-KETO-ESTERS

HOWARTH, T. TREFOR, JACKSON, ANTHONY H., JUDGE, JEAN, KENNER, GEORGE W., NEWMAN, DAVID J.

Journal:

Chemischer Informationsdienst

Year:

1974

File:

PDF, 264 KB

1974

24

ChemInform Abstract: SYNTH. VON BETA-RESORCYLSAEUREN NACH BIOGENETISCHEM MUSTER, ISOLIERUNG UND CHARAKTERISIERUNG DES ALDOL-ZWISCHENPRODUKTS

HOWARTH, T.TREFOR, HARRIS, THOMAS M.

Journal:

Chemischer Informationsdienst. Organische Chemie

Year:

1971

File:

PDF, 169 KB

1971